IM+io Fachmagazin, Ausgabe 2/2025

Was wäre, wenn…: Szenarien der Zelltherapie digital durchgespielt

Literaturhinweise

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[3] Viceconti, Marco; Vos, Maarten de, et al.: Position paper From the digital twins in healthcare to the Virtual Human Twin: a moon-shot project for digital health research. In: IEEE journal of biomedical and health informatics, 2023. 491–501

[4] Rade, Michael; Grieb, Nora, et al.: Single-cell multiomic dissection of response and resistance to chimeric antigen receptor T cells against BCMA in relapsed multiple myeloma. In: Nature cancer, 2024.

[5] Donnadieu, Emmanuel; Luu, Maik, et al.: Time to evolve: predicting engineered T cell-associated toxicity with next-generation models. In: Journal for immunotherapy of cancer, 5/2022.

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[8] Moth, Christopher W.; Sheehan, Jonathan H., et al.: VUStruct: a compute pipeline for high throughput and personalized structural biology. In: bioRxiv, 2024.

[9] Rajeeve, Sridevi; Zahradka, Nicole, et al.: Early and Consistent CRS Detection Using Wearable Device for Remote Patient Monitoring Following CAR-T Therapy in Relapsed/Refractory Multiple Myeloma (RRMM): Early Results of an Investigator-Initiated Trial. In: Blood, Supplement 1/2023. 1007

[10] European Parliament – Regulation EU 2017/745. Medical Device Regulation

[11] European Parliament – Regulation EC No 1394/2007. Regulation on Advanced Therapy Medicinal Products

[12] European Parliament – Regulation EU 2024/1689. Artificial Intelligence Act

[13] European Parliament – Regulation EU 2016/679. General Data Protection Regulation

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Das Projekt CERTAINTY verfolgt das Ziel, die Krebsbehandlung durch personalisierte Medizin zu revolutionieren – insbesondere mittels sogenannter „Virtual Twins“. Mehr dazu erfahren Sie hier: https://www.certainty-virtualtwin.eu/